Shoot them in the face. If you can't shoot them in the face, try the back of the head. When you blow the cerebellum out they'll stop instantly and will also not be able to set any bombs off. You wanna hit the lower part of the brain so like aim for the front teeth or ear.
Also, if you have a gun on you it is a quicker response, getting shot while running to your car, not so good of an idea.
That's a long-winded way of saying "Arm everything."
Good fences make good neighbors and an armed citizenry ensures good citizenry.