It would be a computer I would use for personal use, business use and gaming, so compatibility is extremely important. I'll probably avoid AMD cards for now since I have had so many problems with their drivers in the past. That is my only real requirement. I just haven't had time to do research recently so I'm not sure what some solid Mobos, cases, PSUs, etc. are right now.
As far as CPU's go, I'm using a b450 with a Ryzen 3600 and its working fine. If you do decide to go that route there are some things you might need to know because older stock you will need to flash the bios before it will run the newer ryzens. If you aren't going high end gaming the 2600 is fine and potentially less headache.