So I've done this.
Years ago, probably 10ish. The fan on my GPU crapped out. Rather than deal with trying to mount a new one, I took the side of the case off and blasted everything with a box fan.
The only real downsides I'l can see are dust, noise and perhaps over pressure on sensitive components.
Why spend all that money on a dozen fans? When I can just remove one side and mount this 1600 mm fan?
For real though, is bigger really better?
Is it wise to go with a largest fan possible? What's the pros vs cons?
I've read that a single larger fan is generally quieter than 2 or more smaller fans.
Does anyone have any preferences on fan size?