My biggest issue is there are some people I really want to follow who do youtube unfortunately. Other than that, I could see moving off the grid completely more or less.
I do toy with leaving Youtube though and just taking the hit, would be nice to not participate in ANYTHING the big tech companies produce.
Aside from YouTube, yes I have. But I don't have an account on YouTube, I use NewPipe when viewing on mobile and rarely use my PC these days.
My phone is running LineageOS without any Google apps installed. You can find a lot of decent replacements for google apps on F-Droid.