Ok, 2001 Ford F250 with the 7.3 engine. 363,000 miles.
I knew something was going to get me and it turned out to be the tranny. Theses trucks are notorious for transmission problems.
The question is, how much, on average, will a transmission repair cost? The truck is only worth about $6000. Am I totalled?
Assuming this is an automatic transmission: Check that the transmission dipstick to make sure fluid is still at the correct level. If the fluid level is good, there's a chance you might be looking at a bad torque converter. The good news is that this would be one of the less expensive kinds of transmission repair, though I can only guess at the cost on your particular truck.
If its a manual trans: your clutch might be totally shot. Also one of the less expensive transmission-related repairs.